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Article

Healthy co-twins of patients with affective disorders show reduced risk-related activation of the insula during a monetary gambling task.

Journal of psychiatry & neuroscience : JPN - 1 Jan 2016

Macoveanu Julian, Miskowiak Kamilla, Kessing Lars V, Vinberg Maj, Siebner Hartwig R

Abstract excerpt

BACKGROUND: Healthy first-degree relatives of patients with affective disorders are at increased risk for affective disorders and express discrete structural and functional abnormalities in the brain reward system. However, value-based decision making is not well understood in these at-risk individuals. METHODS: We investigated healthy monozygotic and dizygotic twins with or without a co-twin history of affective...

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Identifiers

PMID: 26395812
DOI: 10.1503/jpn.140220
PMCID: PMC4688027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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