Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adenylate cyclase 5 is required for melanophore and male pattern development in the guppy (Poecilia reticulata).

Pigment cell & melanoma research - 1 Sept 2015

Kottler Verena A, Künstner Axel, Koch Iris, Flötenmeyer Matthias, Langenecker Tobias, Hoffmann Margarete, Sharma Eshita, Weigel Detlef, Dreyer Christine

Abstract excerpt

Guppies (Poecilia reticulata) are colorful fish that have attracted the attention of pigmentation researchers for almost a century. Here, we report that the blond phenotype of the guppy is caused by a spontaneous mutation in the guppy ortholog of adenylate cyclase 5 (adcy5). Using double digest restriction site-associated DNA sequencing (ddRADseq) and quantitative trait locus (QTL) mapping, we linked the blond...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Codon, Terminator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanophores

Share to Melanosomes

Share to Microscopy, Electron, Transmission

Share to Pigmentation

Share to Poecilia

Share to Sex Differentiation

Source

Identifiers

PMID: 26079969
DOI: 10.1111/pcmr.12386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adenylate cyclase 5 is required for melanophore and male pattern development in the guppy (Poecilia reticulata).PMID 26079969Read ↗

Disease association of cyclase-associated protein (CAP): Lessons from gene-targeted mice and human genetic studiesSemantic proximity Read ↗

Genomic consequences of domestication and the diversification of body coloration and morphology in ornamental medaka strains.Semantic proximity Read ↗

Clinical and Molecular Genetics of the Phosphodiesterases (PDEs)Semantic proximity Read ↗

pnp4a Is the Causal Gene of the Medaka Iridophore Mutant guanineless.Semantic proximity Read ↗

Causal gene identification and desirable trait recreation in goldfish.Semantic proximity Read ↗

Genetic basis of orange spot formation in the guppy (Poecilia reticulata).Semantic proximity Read ↗

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes.Semantic proximity Read ↗

Novel mutations in the Myo5a gene cause a dilute coat color phenotype in mice.Semantic proximity Read ↗

A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus.Semantic proximity Read ↗

The Popeye Domain Containing Genes and Their Function as cAMP Effector Proteins in Striated MuscleSemantic proximity Read ↗

<i>Drosophila</i> models of PIGA-CDG mirror patient phenotypesSemantic proximity Read ↗

The PDE-Opathies: Diverse Phenotypes Produced by a Functionally Related Multigene Family.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.