Article
Genomic variability and protein species - Improving sequence coverage for proteogenomics.
Journal of proteomics - 16 Feb 2016
Bischoff Rainer, Permentier Hjalmar, Guryev Victor, Horvatovich Peter
Abstract excerpt
Protein heterogeneity may result from many factors often closely related to the regulation of biological mechanisms. This review addresses one source of protein heterogeneity, the translation of genetic variability and transcriptional modulation to the protein level. We provide an overview how customized protein sequence databases generated using genomic and transcriptomic sequence information in conjunction with...
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