Article
Immunoregulatory effects of bone marrow-derived mesenchymal stem cells in the nasal polyp microenvironment.
Mediators of inflammation - 1 Jan 2014
Pezato Rogério, de Almeida Danilo Cândido, Bezerra Thiago Freire, Silva Fernando de Sá, Perez-Novo Claudina, Gregório Luís Carlos, Voegels Richard Louis, Câmara Niels Olsen, Bachert Claus
Abstract excerpt
Nasal polyposis is a severe, chronic inflammatory condition of the paranasal sinuses and is frequently associated with asthma and aspirin sensitivity. Mesenchymal stem cells exhibit a potent immunosuppressive effect in several inflammatory conditions, and their role in nasal polyposis remains little explored. Hence, we investigated whether bone marrow-derived mesenchymal stem cells could modulate cell phenotype...
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