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A nonhuman primate model of inherited retinal disease

21 Jan 2019

Abstract excerpt

Inherited retinal degenerations are a common cause of untreatable blindness worldwide, with retinitis pigmentosa and cone dystrophy affecting approximately 1 in 3500 and 1 in 10,000 individuals, respectively. A major limitation to the development of effective therapies is the lack of availability of animal models that fully replicate the human condition. Particularly for cone disorders, rodent, canine, and feline...

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PMID: 30667376
DOI: 10.1172/jci123980

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