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Article

Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine.

Gastroenterology - 1 Jan 2016

Knudsen Erik S, O'Reilly Eileen M, Brody Jonathan R, Witkiewicz Agnieszka K

Abstract excerpt

Patients with pancreatic ductal adenocarcinoma (PDA) have a poor prognosis despite new treatments; approximately 7% survive for 5 years. Although there have been advances in systemic, primarily cytotoxic, therapies, it has been a challenge to treat patients with PDA using targeted therapies. Sequence analyses have provided a wealth of information about the genetic features of PDA and have identified potential...

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Identifiers

PMID: 26385075
DOI: 10.1053/j.gastro.2015.08.056
PMCID: PMC5010785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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