Article
Biologically-supported structural model for a viral satellite RNA.
Nucleic acids research - 16 Nov 2015
Ashton Peter, Wu Baodong, D'Angelo Jessica, Grigull Jörg, White K Andrew
Abstract excerpt
Satellite RNAs (satRNAs) are a class of small parasitic RNA replicon that associate with different viruses, including plus-strand RNA viruses. Because satRNAs do not encode a polymerase or capsid subunit, they rely on a companion virus to provide these proteins for their RNA replication and packaging. SatRNAs recruit these and other required factors via their RNA sequences and structures. Here, through a...
Topics
- Models, Molecular
- Mutation
- Nucleic Acid Conformation
- RNA, Satellite
- RNA, Viral
- Tombusvirus