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Article

Primary CNS T-cell Lymphomas: A Clinical, Morphologic, Immunophenotypic, and Molecular Analysis.

The American journal of surgical pathology - 1 Dec 2015

Menon Madhu P, Nicolae Alina, Meeker Hillary, Raffeld Mark, Xi Liqiang, Jegalian Armin G, Miller Douglas C, Pittaluga Stefania, Jaffe Elaine S

Abstract excerpt

Primary central nervous system (CNS) lymphomas are relatively rare with the most common subtype being diffuse large B-cell lymphoma. Primary CNS T-cell lymphomas (PCNSTL) account for <5% of CNS lymphomas. We report the clinical, morphologic, immunophenotypic, and molecular characteristics of 18 PCNSTLs. Fifteen cases were classified as peripheral T-cell lymphoma, not otherwise specified, 2 of which were of γδ...

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Share to Central Nervous System Neoplasms
Share to Gene Rearrangement, delta-Chain T-Cell Antigen Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor

Share to Immunophenotyping

Share to In Situ Hybridization

Share to Lymphoma, T-Cell

Share to Molecular Diagnostic Techniques

Share to Receptors, Antigen, T-Cell, gamma-delta

Source

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Identifiers

PMID: 26379152
DOI: 10.1097/PAS.0000000000000503
PMCID: PMC4644095

Genes

ALK
GNB1
JAK3
KRAS
STAT3
TET2
TIA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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