Article
Mitonuclear linkage disequilibrium in human populations.
Proceedings. Biological sciences - 22 Sept 2015
Sloan Daniel B, Fields Peter D, Havird Justin C
Abstract excerpt
There is extensive evidence from model systems that disrupting associations between co-adapted mitochondrial and nuclear genotypes can lead to deleterious and even lethal consequences. While it is tempting to extrapolate from these observations and make inferences about the human-health effects of altering mitonuclear associations, the importance of such associations may vary greatly among species, depending on...
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