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Article

Variant Profiling of Candidate Genes in Pancreatic Ductal Adenocarcinoma.

Clinical chemistry - 1 Nov 2015

Huang Jiaqi, Löhr Johannes-Matthias, Nilsson Magnus, Segersvärd Ralf, Matsson Hans, Verbeke Caroline, Heuchel Rainer, Kere Juha, Iafrate A John, Zheng Zongli, Ye Weimin

Abstract excerpt

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis. Variant profiling is crucial for developing personalized treatment and elucidating the etiology of this disease. METHODS: Patients with PDAC undergoing surgery from 2007 to 2012 (n = 73) were followed from diagnosis until death or the end of the study. We applied an anchored multiplex PCR (AMP)-based next-generation sequencing (NGS) method...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26378065
DOI: 10.1373/clinchem.2015.238543

Genes

KRAS
SMAD4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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