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Article

Aseptic Raman spectroscopy can detect changes associated with the culture of human dental pulp stromal cells in osteoinductive culture.

The Analyst - 7 Nov 2015

Mitchell Adam, Ashton Lorna, Yang Xuebin B, Goodacre Royston, Tomlinson Matthew J, Smith Alistair, Kirkham Jennifer

Abstract excerpt

There is an unmet need for the non-invasive characterisation of stem cells to facilitate the translation of cell-based therapies. Raman spectroscopy has proven utility in stem cell characterisation but as yet no method has been reported capable of taking repeated Raman measurements of living cells aseptically over time. The aim of this study was to determine if Raman spectroscopy could be used to monitor changes...

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Identifiers

PMID: 26374253
DOI: 10.1039/c5an01595b
PMCID: PMC4621535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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