Article
REM sleep behavior disorder, as assessed by questionnaire, in G2019S LRRK2 mutation PD and carriers.
Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2015
Saunders-Pullman Rachel, Alcalay Roy N, Mirelman Anat, Wang Cuiling, Luciano Marta San, Ortega Roberto A, Glickman Amanda, Raymond Deborah, Mejia-Santana Helen, Doan Nancy, Johannes Brooke, Yasinovsky Kira, Ozelius Laurie, Clark Lorraine, Orr-Utreger Avi, Marder Karen, Giladi Nir, Bressman Susan B
Abstract excerpt
BACKGROUND: Rapid eye movement sleep behavior disorder occurs with idiopathic Parkinson's disease (PD) and often precedes PD. Its frequency in LRRK2-PD and utility as a preclinical marker has not been established. METHODS: One hundred forty-four idiopathic PD, 142 LRRK2 G2019S mutation PD, 117 non-manifesting carriers, 93 related noncarriers, and 40 healthy controls completed the Rapid eye movement sleep Behavior...
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