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Article

Comprehensive tissue-specific gene set enrichment analysis and transcription factor analysis of breast cancer by integrating 14 gene expression datasets.

Oncotarget - 24 Jan 2017

Li Wen-Xing, He Kan, Tang Ling, Dai Shao-Xing, Li Gong-Hua, Lv Wen-Wen, Guo Yi-Cheng, An San-Qi, Wu Guo-Ying, Liu Dahai, Huang Jing-Fei

Abstract excerpt

Breast cancer is the most commonly diagnosed malignancy in women. Several key genes and pathways have been proven to correlate with breast cancer pathology. This study sought to explore the differences in key transcription factors (TFs), transcriptional regulation networks and dysregulated pathways in different tissues in breast cancer. We employed 14 breast cancer datasets from NCBI-GEO and performed an...

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PMID: 28036274
DOI: 10.18632/oncotarget.14286
PMCID: PMC5351668

Genes

ATOH8
DMRT2
EGR1
EGR2
EGR3
FOS
FOSB
NFIL3
TBX15

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