Article
Differences in Expression of DPP4 in Steatotic Rat Liver Are Not Related to Differences in the Methylation of its Gene Promoter.
In vivo (Athens, Greece) - 1 Jan 2000
Tarantola Eleonora, Gobbato Sara, Ferrigno Andrea, Bertone Vittorio, Capelli Enrica
Abstract excerpt
The aim of the present study was to investigate the methylation status in the promoter region of Dipeptidyl peptidase-IV (Dpp4) gene, in livers from obese Zucker rats with different patterns of immunohistochemical positivity. Molecular analysis was carried-out on DNA obtained from livers of obese and lean Zucker rats and of control Wistar rats using the bisulfite conversion method and DNA sequencing. Our study...
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