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Article

Triple-layer dissection of the lung adenocarcinoma transcriptome: regulation at the gene, transcript, and exon levels.

Oncotarget - 6 Oct 2015

Hsu Min-Kung, Wu I-Ching, Cheng Ching-Chia, Su Jen-Liang, Hsieh Chang-Huain, Lin Yeong-Shin, Chen Feng-Chi

Abstract excerpt

Lung adenocarcinoma is one of the most deadly human diseases. However, the molecular mechanisms underlying this disease, particularly RNA splicing, have remained underexplored. Here, we report a triple-level (gene-, transcript-, and exon-level) analysis of lung adenocarcinoma transcriptomes from 77 paired tumor and normal tissues, as well as an analysis pipeline to overcome genetic variability for accurate...

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Identifiers

PMID: 26356813
DOI: 10.18632/oncotarget.4810
PMCID: PMC4745690

Genes

DAP3
ETV4
GABARAPL1
GDF10
LYVE1
RADIL
RASIP1
RNF5
RSPO1
SERTM1
SRPK1
TNXB
TRIM27

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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