Article
Systematic identification of cancer-related long noncoding RNAs and aberrant alternative splicing of quintuple-negative lung adenocarcinoma through RNA-Seq.
Lung cancer (Amsterdam, Netherlands) - 1 Jul 2017
Zhang Lu, Li Shiyong, Choi Yoon-La, Lee Jinseon, Gong Zhuolin, Liu Xiaoqiao, Pei Yunfei, Jiang Awei, Ye Mingzhi, Mao Mao, Zhang Xuegong, Kim Jhingook, Chen Ronghua
Abstract excerpt
OBJECTIVES: Lung adenocarcinoma (LUAD) is a common subtype of non-small cell lung cancer prevalent in Asia. There is a dearth of understanding regarding the transcriptome landscape of LUAD without primary known driver mutations. In this study, LUAD samples without well-known driver mutations occurring in EGFR, KRAS, ALK, ROS1 or RET (quintuple-negative) were used for transcriptome study with a focus on long...
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