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Article

S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma.

BMC cancer - 9 Sept 2015

Sapkota Dipak, Bruland Ove, Parajuli Himalaya, Osman Tarig A, Teh Muy-Teck, Johannessen Anne C, Costea Daniela Elena

Abstract excerpt

BACKGROUND: Altered expression of S100A16 has been reported in human cancers, but its biological role in tumorigenesis is not fully understood. This study aimed to investigate the clinical significance and functional role of S100A16 in oral squamous cell carcinoma (OSCC) suppression. METHODS: S100A16 mRNA and/or protein levels were examined by quantitative RT-PCR and immunohistochemistry in whole- and laser...

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Source

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Identifiers

PMID: 26353754
DOI: 10.1186/s12885-015-1622-1
PMCID: PMC4564982

Genes

MMP1
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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