Article
mRNA overexpression of kallikrein-related peptidase 14 (KLK14) is an independent predictor of poor overall survival in chronic lymphocytic leukemia patients.
Clinical chemistry and laboratory medicine - 1 Feb 2016
Kontos Christos K, Adamopoulos Panagiotis G, Papageorgiou Sotirios G, Pappa Vassiliki, Scorilas Andreas
Abstract excerpt
BACKGROUND: Tissue kallikrein and kallikrein-related peptidases (KLKs) compose a family of serine endopeptidases with much clinical interest in oncology, as their potential as diagnostic and/or prognostic molecular biomarkers in several human malignancies has already been evidenced. However, none of the members of this family has ever been studied in hematological malignancies. Based on our preliminary results...
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