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Mitochondrial metabolism in cancer stem cells: a therapeutic target for colon cancer

31 Oct 2015

Abstract excerpt

It has been proposed that the selective elimination of cancer stem cells (CSCs) using targeted therapy could greatly reduce tumor growth, recurrence, and metastasis. To develop effective therapeutic targets for CSC elimination, we aimed to define the properties of CSC mitochondria, and identify CSC-mitochondria- specific targets in colon cancer. We found that colon CSCs utilize mitochondrial oxidative...

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PMID: 26350748
DOI: 10.5483/bmbrep.2015.48.10.179

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