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Article

Hallmarks of cancer stem cell metabolism

24 May 2016

Abstract excerpt

Cancer cells adapt cellular metabolism to cope with their high proliferation rate. Instead of primarily using oxidative phosphorylation (OXPHOS), cancer cells use less efficient glycolysis for the production of ATP and building blocks (Warburg effect). However, tumours are not uniform, but rather functionally heterogeneous and harbour a subset of cancer cells with stemness features. Such cancer cells have the...

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PMID: 27219018
DOI: 10.1038/bjc.2016.152

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