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Novel Immune Check-Point Regulators in Tolerance Maintenance

18 Aug 2015

Abstract excerpt

The great success of anti-cytotoxic lymphocyte antigen 4 (CTLA4) and anti-programed cell death protein 1 (PD1) in cancer treatment has encouraged more effort in harnessing the immune response through immunomodulatory molecules in various diseases. The immunoglobulin (Ig) super family comprises the majority of immunomodulatory molecules. Discovery of novel Ig super family members has brought novel insights into...

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PMID: 26347744
DOI: 10.3389/fimmu.2015.00421

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