Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VISTA: A Promising Target for Cancer Immunotherapy?

1 Jun 2021

Abstract excerpt

Agents targeting the B7 family co-inhibitory receptors cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed cell death protein-1 (PD-1), or its ligand (PD-L1), have a pivotal role in clinical practice. V-domain Ig suppressor of T-cell activation (VISTA) is a protein highly conserved between species, with a similar amino acid sequence to the B7 family members, characterized by a particularly structural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to CAR-T cell therapy research
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34189130
DOI: 10.2147/itt.s260429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VISTA: A Promising Target for Cancer Immunotherapy?PMID 34189130Read ↗

VISTA expression and patient selection for immune-based anticancer therapySemantic proximity Read ↗

Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlightsSemantic proximity Read ↗

VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapySemantic proximity Read ↗

VISTA-mediated immune evasion in cancerSemantic proximity Read ↗

Immunoregulatory functions of VISTASemantic proximity Read ↗

V-Set and immunoglobulin domain containing (VSIG) proteins as emerging immune checkpoint targets for cancer immunotherapySemantic proximity Read ↗

Structure and Functional Binding Epitope of V-domain Ig Suppressor of T Cell ActivationSemantic proximity Read ↗

VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responsesSemantic proximity Read ↗

Tumor immune checkpoints and their associated inhibitorsSemantic proximity Read ↗

Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4Semantic proximity Read ↗

The Expression Pattern and Clinical Significance of the Immune Checkpoint Regulator VISTA in Human Breast CancerSemantic proximity Read ↗

New B7 Family Checkpoints in Human CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.