Article
Transcriptional Pathways in cPGI2-Induced Adipocyte Progenitor Activation for Browning
17 Aug 2015
Abstract excerpt
De novo formation of beige/brite adipocytes from progenitor cells contributes to the thermogenic adaptation of adipose tissue and holds great potential for the therapeutic remodeling of fat as a treatment for obesity. Despite the recent identification of several factors regulating browning of white fat, there is a lack of physiological cell models for the mechanistic investigation of progenitor-mediated...
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