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Differentiation of early germ cells from human skin-derived stem cells without exogenous gene integration

8 Sept 2015

Abstract excerpt

Infertility has long been a difficult issue for many couples. The successful differentiation of germ cells and live progeny from pluripotent stem cells brings new hope to the couples suffering with infertility. Here we successfully isolated human fetus skin-derived stem cells (hfSDSCs) from fetus skin tissue and demonstrated that hfSDSCs can be differentiated into early human germ cell-like cells (hGCLCs). These...

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PMID: 26347377
DOI: 10.1038/srep13822

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