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Article

The Current State and Future Development of Epigenetic Toxicology.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Jan 2017

Igarashi Katsuhide, Ideta-Otsuka Maky, Narita Minoru

Abstract excerpt

Epigenetics has drawn much attention as a mechanism of transcriptional regulation involving modifications to genomic DNA and histone, without changes to nucleotide sequences. Epigenetics is related to various biological phenomena. We defined one of these phenomena as "epigenetic toxicity", in which chemicals affect epigenetic regulation and result in undesirable effects on living organisms. We then detailed the...

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PMID: 28250319
DOI: 10.1248/yakushi.16-00230-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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