Article
BRAF V600E and decreased NIS and TPO expression are associated with aggressiveness of a subgroup of papillary thyroid microcarcinoma.
European journal of endocrinology - 1 Oct 2015
Bastos André Uchimura, Oler Gisele, Nozima Bruno Heidi Nakano, Moysés Raquel Ajub, Cerutti Janete Maria
Abstract excerpt
BACKGROUND: Thyroid cancer incidence has dramatically increased worldwide over the last two decades. The rise is mostly due to an increased detection of small papillary thyroid carcinomas (PTCs) (≤20 mm), predominantly microPTC (≤10 mm). Although small tumors generally have an excellent outcome, a considerable percentage may have a more aggressive disease and worse prognosis. The clinical challenge is to...
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