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Article

Gene polymorphism of thymidine kinase and DNA polymerase in clinical strains of herpes simplex virus.

Antiviral therapy - 1 Jan 2011

Bohn Kathrin, Zell Roland, Schacke Michael, Wutzler Peter, Sauerbrei Andreas

Abstract excerpt

BACKGROUND: The thymidine kinase (TK) and DNA polymerase (pol) genes of herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are important targets for genotypic determination of HSV resistance to antiviral drugs. The knowledge of gene polymorphism is an absolute requirement for the correct interpretation of genotypic findings. METHODS: In this study, the natural polymorphism of TK and DNA pol genes was examined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22024514
DOI: 10.3851/IMP1852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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