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Article

Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans.

Journal of medical genetics - 1 Nov 2015

Hsu Yi-Hsiang, Liu Youfang, Hannan Marian T, Maixner William, Smith Shad B, Diatchenko Luda, Golightly Yvonne M, Menz Hylton B, Kraus Virginia B, Doherty Michael, Wilson A G, Jordan Joanne M

Abstract excerpt

OBJECTIVE: Hallux valgus (HV) affects ∼36% of Caucasian adults. Although considered highly heritable, the underlying genetic determinants are unclear. We conducted the first genome-wide association study (GWAS) aimed to identify genetic variants associated with HV. METHODS: HV was assessed in three Caucasian cohorts (n=2263, n=915 and n=1231 participants, respectively). In each cohort, a GWAS was conducted using...

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Identifiers

PMID: 26337638
DOI: 10.1136/jmedgenet-2015-103142
PMCID: PMC4864963

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AXIN2
ESD
MRGPRX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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