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Article

Molecular Dynamics Simulation Reveals the Selective Binding of Human Leukocyte Antigen Alleles Associated with Behçet's Disease.

PloS one - 1 Jan 2015

Kongkaew Sirilak, Yotmanee Pathumwadee, Rungrotmongkol Thanyada, Kaiyawet Nopporn, Meeprasert Arthitaya, Kaburaki Toshikatsu, Noguchi Hiroshi, Takeuchi Fujio, Kungwan Nawee, Hannongbua Supot

Abstract excerpt

Behçet's disease (BD), a multi-organ inflammatory disorder, is associated with the presence of the human leukocyte antigen (HLA) HLA-B*51 allele in many ethnic groups. The possible antigen involvement of the major histocompatibility complex class I chain related gene A transmembrane (MICA-TM) nonapeptide (AAAAAIFVI) has been reported in BD symptomatic patients. This peptide has also been detected in HLA-A*26:01...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26331842
DOI: 10.1371/journal.pone.0135575
PMCID: PMC4557978

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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