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Article

Randomized Trial of Benznidazole for Chronic Chagas' Cardiomyopathy.

The New England journal of medicine - 1 Oct 2015

Morillo Carlos A, Marin-Neto Jose Antonio, Avezum Alvaro, Sosa-Estani Sergio, Rassi Anis, Rosas Fernando, Villena Erick, Quiroz Roberto, Bonilla Rina, Britto Constança, Guhl Felipe, Velazquez Elsa, Bonilla Laura, Meeks Brandi, Rao-Melacini Purnima, Pogue Janice, Mattos Antonio, Lazdins Janis, Rassi Anis, Connolly Stuart J, Yusuf Salim

Abstract excerpt

BACKGROUND: The role of trypanocidal therapy in patients with established Chagas' cardiomyopathy is unproven. METHODS: We conducted a prospective, multicenter, randomized study involving 2854 patients with Chagas' cardiomyopathy who received benznidazole or placebo for up to 80 days and were foll...

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Source

Identifiers

PMID: 26323937
DOI: 10.1056/NEJMoa1507574

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26323937-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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