Article
Role of penA polymorphisms for penicillin susceptibility in Neisseria lactamica and Neisseria meningitidis.
International journal of medical microbiology : IJMM - 1 Oct 2015
Karch André, Vogel Ulrich, Claus Heike
Abstract excerpt
In meningococci, reduced penicillin susceptibility is associated with five specific mutations in the transpeptidase region of penicillin binding protein 2 (PBP2). We showed that the same set of mutations was present in 64 of 123 Neisseria lactamica strains obtained from a carriage study (MIC range: 0.125-2.0mg/L). The PBP2 encoding penA alleles in these strains were genetically similar to those found in...
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