Article
The invasive MenC cc103 lineage with penicillin reduced susceptibility persisting in Brazil.
International journal of medical microbiology : IJMM - 1 Sept 2017
Fonseca Érica L, Marin Michel A, Freitas Fernanda S, Vitório Bruna S A, de Araújo Flávio M G, Camargo Dhian R A, Coimbra Roney S, De Filippis Ivano R, Vicente Ana Carolina P
Abstract excerpt
Penicillin is the antibiotic of choice for the treatment of meningococcal infections, and mutations in penA gene are involved with reduced susceptibility (penI) emergence to this antibiotic. This study aimed to characterize the penA allelic diversity, their association with penI phenotype and distribution among prevalent meningococci serogroups in Brazil. The entire penA from 49 invasive strains of distinct...
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