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Article

Polymorphism of Neisseria meningitidis penA gene associated with reduced susceptibility to penicillin.

The Journal of antimicrobial chemotherapy - 1 Mar 2001

Antignac A, Kriz P, Tzanakaki G, Alonso J M, Taha M K

Abstract excerpt

We studied polymorphism of penA (which encodes penicillin-binding protein 2) in 13 strains of Neisseria meningitidis susceptible to penicillin (pen(S)) and 12 strains with reduced susceptibility to penicillin (pen(I)). These strains differed in geographical origin. Serological and genetic typing showed that they were highly diverse and belonged to several genetic lineages. Restriction analysis and DNA sequencing...

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Identifiers

PMID: 11222561
DOI: 10.1093/jac/47.3.285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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