Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coupling the modules of EMT and stemness: A tunable 'stemness window' model.

Oncotarget - 22 Sept 2015

Jolly Mohit Kumar, Jia Dongya, Boareto Marcelo, Mani Sendurai A, Pienta Kenneth J, Ben-Jacob Eshel, Levine Herbert

Abstract excerpt

Metastasis of carcinoma involves migration of tumor cells to distant organs and initiate secondary tumors. Migration requires a complete or partial Epithelial-to-Mesenchymal Transition (EMT), and tumor-initiation requires cells possessing stemness. Epithelial cells (E) undergoing a complete EMT to become mesenchymal (M) have been suggested to be more likely to possess stemness. However, recent studies suggest...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epithelial-Mesenchymal Transition
Share to Homeodomain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNAs

Share to Neoplastic Stem Cells

Share to NF-kappa B

Share to RNA-Binding Proteins

Share to Snail Family Transcription Factors

Share to Zinc Finger E-box-Binding Homeobox 1

Source

Open in PubMed Open full text

Identifiers

PMID: 26317796
DOI: 10.18632/oncotarget.4629
PMCID: PMC4694822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coupling the modules of EMT and stemness: A tunable 'stemness window' model.PMID 26317796Read ↗

Hybrid E/M phenotype(s) and stemness: a mechanistic connection embedded in network topologySemantic proximity Read ↗

Hybrid E/M Phenotype(s) and Stemness: A Mechanistic Connection Embedded in Network TopologySemantic proximity Read ↗

A mechanism-based computational model to capture the interconnections among epithelial-mesenchymal transition, cancer stem cells and Notch-Jagged signalingSemantic proximity Read ↗

The Epithelial-Mesenchymal Transition and Cancer Stem Cells: Functional and Mechanistic LinksSemantic proximity Read ↗

A mechanism-based computational model to capture the interconnections among epithelial-mesenchymal transition, cancer stem cells and Notch-Jagged signalingSemantic proximity Read ↗

An Ovol2-Zeb1 Mutual Inhibitory Circuit Governs Bidirectional and Multi-step Transition between Epithelial and Mesenchymal StatesSemantic proximity Read ↗

Heterogeneity and plasticity of epithelial–mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanismsSemantic proximity Read ↗

Concise Review: Stem Cells and Epithelial-Mesenchymal Transition in Cancer: Biological Implications and Therapeutic TargetsSemantic proximity Read ↗

Reconstruction of single-cell lineage trajectories and identification of diversity in fates during the epithelial-to-mesenchymal transitionSemantic proximity Read ↗

Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progressionSemantic proximity Read ↗

Quantifying Cancer Epithelial-Mesenchymal Plasticity and Its Association with Stemness and Immune ResponseSemantic proximity Read ↗

Epithelial to Mesenchymal Transition: A Challenging Playground for Translational Research. Current Models and Focus on TWIST1 Relevance and Gastrointestinal CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.