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Article

Serological proteome analysis reveals new specific biases in the IgM and IgG autoantibody repertoires in autoimmune polyendocrine syndrome type 1.

Autoimmunity - 1 Jan 2015

Dubucquoi Sylvain, Proust-Lemoine Emmanuelle, Kemp E Helen, Ryndak Amélie, Lefèvre-Dutoit Virginie, Bellart Marine, Saugier-Véber Pascale, Duban-Deweer Sophie, Wémeau Jean-Louis, Prin Lionel, Lefranc Didier

Abstract excerpt

OBJECTIVE: Autoimmune polyendocrine syndrome type 1 (APS 1) is caused by mutations in the AIRE gene that induce intrathymic T-cell tolerance breakdown, which results in tissue-specific autoimmune diseases. DESIGN: To evaluate the effect of a well-defined T-cell repertoire impairment on humoral se...

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Source

Identifiers

PMID: 26312540
DOI: 10.3109/08916934.2015.1077230

Genes

AIRE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26312540-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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