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Article

Immunogenicity of autoantigens.

BMC genomics - 4 Jul 2011

Backes Christina, Ludwig Nicole, Leidinger Petra, Harz Christian, Hoffmann Jana, Keller Andreas, Meese Eckart, Lenhof Hans-Peter

Abstract excerpt

BACKGROUND: Autoantibodies against self-antigens have been associated not only with autoimmune diseases, but also with cancer and are even found in healthy individuals. The mechanism causing the autoantibody response remains elusive for the majority of the immunogenic antigens. To deepen the understanding of autoantibody responses, we ask whether natural-occurring, autoimmunity-associated and tumor-associated...

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Identifiers

PMID: 21726451
DOI: 10.1186/1471-2164-12-340
PMCID: PMC3149588

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