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Article

Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion.

Journal of virology - 1 Nov 2015

Stapleford Kenneth A, Rozen-Gagnon Kathryn, Das Pratyush Kumar, Saul Sirle, Poirier Enzo Z, Blanc Hervé, Vidalain Pierre-Olivier, Merits Andres, Vignuzzi Marco

Abstract excerpt

UNLABELLED: To date, the majority of work on RNA virus replication fidelity has focused on the viral RNA polymerase, while the potential role of other viral replicase proteins in this process is poorly understood. Previous studies used resistance to broad-spectrum RNA mutagens, such as ribavirin,...

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Source

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Identifiers

PMID: 26311883
DOI: 10.1128/JVI.01553-15
PMCID: PMC4645662

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26311883-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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