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Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

27 Aug 2015

Abstract excerpt

A longstanding and still-increasing threat to the effective treatment of infectious diseases is resistance to antimicrobial countermeasures. Potentially, the targeting of host proteins and pathways essential for the detrimental effects of pathogens offers an approach that may discover broad-spectrum anti-pathogen countermeasures and circumvent the effects of pathogen mutations leading to resistance. Here we...

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PMID: 26310922
DOI: 10.1038/srep13476

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