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Medicinal chemistry strategies toward host targeting antiviral agents

14 Feb 2020

Abstract excerpt

Direct-acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and have been demonstrated to be very successful in combating viral infections in clinic. However, DAAs suffer from several inherent limitations, including narrow-spectrum antiviral profiles and liability to drug resistance, and hence there are still unmet needs in the treatment of viral infections. In comparison, host...

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PMID: 32060956
DOI: 10.1002/med.21664

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