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Article

TIGIT negatively regulates inflammation by altering macrophage phenotype.

Immunobiology - 1 Jan 2016

Chen Xi, Lu Pu-Han, Liu Lei, Fang Ze-Min, Duan Wu, Liu Zhe-Long, Wang Cong-Yi, Zhou Ping, Yu Xue-Feng, He Wen-Tao

Abstract excerpt

Macrophages function as an essential component of innate immune system, contributing to both the initiation and appropriate resolution of inflammation. The exposure of macrophages to the microbial products, such as lipopolysaccharide (LPS), can strongly shift the balance between tissue homeostasi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26307002
DOI: 10.1016/j.imbio.2015.08.003

Genes

TIGIT
PVR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26307002-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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