Article
Target specificity among canonical nuclear poly(A) polymerases in plants modulates organ growth and pathogen response.
Proceedings of the National Academy of Sciences of the United States of America - 20 Aug 2013
Vi Son Lang, Trost Gerda, Lange Peggy, Czesnick Hjördis, Rao Nishta, Lieber Diana, Laux Thomas, Gray William M, Manley James L, Groth Detlef, Kappel Christian, Lenhard Michael
Abstract excerpt
Polyadenylation of pre-mRNAs is critical for efficient nuclear export, stability, and translation of the mature mRNAs, and thus for gene expression. The bulk of pre-mRNAs are processed by canonical nuclear poly(A) polymerase (PAPS). Both vertebrate and higher-plant genomes encode more than one isoform of this enzyme, and these are coexpressed in different tissues. However, in neither case is it known whether the...
Topics
- Active Transport, Cell Nucleus
- Arabidopsis
- Arabidopsis Proteins
- Gene Expression Regulation, Plant
- Genotype
- Microarray Analysis
- Mutation
- Plant Leaves
- Polynucleotide Adenylyltransferase