Article
Structure-Function Relationships of Class D Carbapenemases.
Current drug targets - 1 Jan 2016
Docquier Jean-Denis, Mangani Stefano
Abstract excerpt
Class D carbapenemases, also known as Carbapenem-Hydrolyzing class D β-Lactamases (CHDLs) are of increasingly high clinical relevance, as they have been found in various important human pathogens, such as Acinetobacter baumannii and Klebsiella pneumoniae and contribute to the evolution of these pathogens towards extensively or totally-drug resistance (XDR/TDR) phenotypes. Essentially two main groups of...
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