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Article

Genetic abnormalities of the EGFR pathway in African American Patients with non-small-cell lung cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Nov 2009

Leidner Rom S, Fu Pingfu, Clifford Bradley, Hamdan Ayad, Jin Cheng, Eisenberg Rosana, Boggon Titus J, Skokan Margaret, Franklin Wilbur A, Cappuzzo Federico, Hirsch Fred R, Varella-Garcia Marileila, Halmos Balazs

Abstract excerpt

PURPOSE: Previous studies in non-small-cell lung cancer (NSCLC) have demonstrated a wide variation in responsiveness to epidermal growth factor receptor (EGFR) -targeting agents and in genetic aberrancies of the EGFR pathway according to ethnic background, most notably a higher frequency of activ...

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Identifiers

PMID: 19786660
DOI: 10.1200/JCO.2009.23.1431
PMCID: PMC3329938

Genes

EGFR
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19786660-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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