Article
Tryptophan probes reveal residue-specific phospholipid interactions of apolipoprotein C-III.
Biochimica et biophysica acta - 1 Nov 2015
Pfefferkorn Candace M, Walker Robert L, He Yi, Gruschus James M, Lee Jennifer C
Abstract excerpt
Apolipoproteins are essential human proteins for lipid metabolism. Together with phospholipids, they constitute lipoproteins, nm to μm sized particles responsible for transporting cholesterol and triglycerides throughout the body. To investigate specific protein-lipid interactions, we produced and characterized three single-Trp containing apolipoprotein C-III (ApoCIII) variants (W42 (W54F/W65F), W54 (W42F/W65F),...
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