Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Next-generation sequencing for genetic testing of familial colorectal cancer syndromes

20 Aug 2015

Abstract excerpt

BACKGROUND: Genetic screening in families with high risk to develop colorectal cancer (CRC) prevents incurable disease and permits personalized therapeutic and follow-up strategies. The advancement of next-generation sequencing (NGS) technologies has revolutionized the throughput of DNA sequencing. METHODS: A series of 16 probands for either familial adenomatous polyposis (FAP; 8 cases) or hereditary nonpolyposis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Genetic factors in colorectal cancer
Share to Genomics and Rare Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26300997
DOI: 10.1186/s13053-015-0039-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Next-generation sequencing for genetic testing of familial colorectal cancer syndromesPMID 26300997Read ↗

Improving Mutation Screening in Patients with Colorectal Cancer Predisposition Using Next-Generation Sequencing.Semantic proximity Read ↗

Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations.Semantic proximity Read ↗

Targeted next-generation sequencing as a diagnostic tool in gastrointestinal system cancer/polyposis patients.Semantic proximity Read ↗

Targeted sequencing of 36 known or putative colorectal cancer susceptibility genesSemantic proximity Read ↗

Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients.Semantic proximity Read ↗

Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.Semantic proximity Read ↗

Canonical and uncanonical pathogenic germline variants in colorectal cancer patients by next-generation sequencing in a European referral center.Semantic proximity Read ↗

Comprehensive analysis of germline mutations in northern Brazil: a panel of 16 genes for hereditary cancer-predisposing syndrome investigation.Semantic proximity Read ↗

Next-generation sequencing with comprehensive bioinformatics analysis facilitates somatic mosaic APC gene mutation detection in patients with familial adenomatous polyposisSemantic proximity Read ↗

Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.Semantic proximity Read ↗

Exome sequencing of familial adenomatous polyposis-like individuals identifies both known and novel causative genes.Semantic proximity Read ↗

Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.