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Article

Discovering functional DNA elements using population genomic information: a proof of concept using human mtDNA.

Genome biology and evolution - 9 Jun 2014

Schrider Daniel R, Kern Andrew D

Abstract excerpt

Identifying the complete set of functional elements within the human genome would be a windfall for multiple areas of biological research including medicine, molecular biology, and evolution. Complete knowledge of function would aid in the prioritization of loci when searching for the genetic bases of disease or adaptive phenotypes. Because mutations that disrupt function are disfavored by natural selection,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24916662
DOI: 10.1093/gbe/evu116
PMCID: PMC4122919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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