Article
Frequency of transmitted drug resistance mutations among treatment-naïve HIV-1-infected individuals at a tertiary care centre in South India.
Molecular diagnosis & therapy - 1 Oct 2015
Kannangai Rajesh, David Shoba, Sundaresan Vijayanand C, Sachithanandham Jaiprasath, Mani Monika, Abraham Ooriapadickal Cherian, Pulimood Susanne Alexander, Rupali Priscilla, Sridharan Gopalan
Abstract excerpt
INTRODUCTION: Morbidity and mortality among HIV-1-infected individuals has been dramatically reduced by the implementation of combinational antiretroviral therapy (ART). However, the efficiency of these therapies is compromised due to HIV-1 transmitted drug resistance mutations (TDRMs). METHODS: We collected a total of 127 samples from ART-naïve HIV-infected individuals and sequenced the pol gene and analysed for...
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