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Transmitted Drug Resistance Among Recently Diagnosed Adults and Children in São Paulo, Brazil.

AIDS research and human retroviruses - 1 Dec 2015

Guimarães Paula Morena de Souza, Ferreira João Leandro de Paula, Coelho Luana Portes Ozório, Cavalcanti Jaqueline de Souza, Lopes Giselle Ibette Silva Lopez, Matsuda Elaine Monteiro, Almeida Flávia Jacqueline, Almeida Valéria Correia, Campeas Alexandre Ely, Junior Luiz Carlos Pereira, Brígido Luís Fernando de Macedo

Abstract excerpt

Transmitted drug resistance mutations (TDRM) have been a constant threat to treatment efficacy. We evaluated TDRM in plasma RNA of 217 antiretroviral therapy-naive patients from sites in the São Paulo metropolitan area, collected from 2012 to 2014. The partial HIV-1 polymerase region was sequenced using Big Dye terminators at an ABI 3130 Genetic Analyzer. TDRM was defined according to the Stanford database...

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Identifiers

PMID: 25826640
DOI: 10.1089/AID.2014.0354

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