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Article

PD-1/PD-L1 signal pathway participates in HCV F protein-induced T cell dysfunction in chronic HCV infection.

Immunologic research - 1 Apr 2016

Xiao Wen, Jiang Long Feng, Deng Xiao Zhao, Zhu Dan Yan, Pei Jia Ping, Xu Mao Lei, Li Bing Jun, Wang Chang Jun, Zhang Jing Hai, Zhang Qi, Zhou Zhen Xian, Ding Wei Liang, Xu Xiao Dong, Yue Ming

Abstract excerpt

Programmed cell death-1/programmed cell death-1 ligand 1 (PD-1/PD-L1) inhibitory signal pathway has been verified to be involved in the establishment of persistent viral infections. Blockade of PD-1/PD-L1 engagement to reinvigorate T cell activity is supposed to be a potential therapeutic scheme. Studies have verified the participation of PD-1/PD-L1 in hepatitis C virus (HCV) core protein-regulated immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26286967
DOI: 10.1007/s12026-015-8680-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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