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Article

Cancer Signature Investigation: ERBB2 (HER2)-Activating Mutation and Amplification-Positive Breast Carcinoma Mimicking Lung Primary.

Journal of the National Comprehensive Cancer Network : JNCCN - 1 Aug 2015

Shih Jennifer, Bashir Babar, Gustafson Karen S, Andrake Mark, Dunbrack Roland L, Goldstein Lori J, Boumber Yanis

Abstract excerpt

Next-generation sequencing of primary and metachronous metastatic cancer lesions may impact patient care. We present a case of relapsed metastatic breast cancer with a dominant pulmonary lesion originally identified as lung adenocarcinoma. A 72-year-old, never-smoker woman with a protracted cough was found to have a large lung mass and regional lymphadenopathy on a chest CT. Lung mass biopsy showed adenocarcinoma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26285240
DOI: 10.6004/jnccn.2015.0115
PMCID: PMC4763101

Genes

ERBB2
SMARCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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